Lab Chemical
SODIUM Tert BUTOXIDE 98%
SKU: RXSOL-60-6605-580
Sodium tert-butoxide, 98% cAS 865-48-5 - used as a strong base and a non-nucleophilic base. In organic synthesis, it serves as an intermediate in various reactions like condensation, rearrangement and ring-opening.
Application
It is useful in dehydrohalogenation reactions. Potassium tert-butoxide catalyzes the reaction of hydrosilanes and heterocyclic compounds to give the silyl derivatives, with release of H2
Dosage
tert-butoxide can be used to form the “less substituted” alkenes in elimination reactions (the E2, specifically). Most of the time, elimination reactions favor the “more substituted” alkene – that is, the Zaitsev product
